Influence of different supplementation on platelet aggregation in patients with rheumatoid arthritis.

Introduction: Long-chain n-3 polyunsaturated fatty acids (n-3 PUFAs; eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)) have been reported to reduce platelet aggregation. Our aim was to prospectively assess the potential influence of different supplementation omega-3 PUFA on the antiplatelet effects in rheumatoid arthritis (RA) patients.

Methods: The study included 60 patients with RA at the Department of Rheumatology, Clinical Center Kragujevac.