Synopsis of recent research by authors named "Marija Adzic"
- Marija Adzic's recent research focuses on the roles of extracellular matrix proteins, particularly tenascin-C, and purinergic signaling in central nervous system (CNS) injury and neuroinflammation, suggesting that modulation of these pathways could enhance recovery and understanding of neurodegenerative diseases.
- Major findings indicate that the absence of tenascin-C leads to increased microglial proliferation and delayed astrocytic response in CNS injuries, while further studies demonstrate that abnormal expression of ectonucleotidases, such as NTPDase2, correlates with neuroinflammatory conditions, impacting neuronal health and function.
- Adzic's work also explores therapeutic potentials of non-invasive techniques like repetitive transcranial magnetic stimulation (rTMS) to alleviate cognitive deficits and neuroinflammation in models of Alzheimer's disease and multiple sclerosis, highlighting the significance of purinergic mechanisms in neuroprotection.
