Publications by authors named "Mariia P Pestriakova"
Free Radic Biol Med
November 2023
Article Synopsis
- Diabetes increases the risk of ischemic stroke by worsening cerebral damage due to hyperglycemia, though the exact mechanisms are not fully understood.
- This study presents novel findings on the real-time dynamics of hydrogen peroxide (HO) in neuronal mitochondria during ischemic stroke, using advanced technology on both cultured cells and rat brains.
- Results indicate that high blood sugar doesn't impact HO generation in the ischemic area but does worsen the overall effects of the stroke, revealing how elevated glucose levels can alter mitochondrial function in neurons.
