Publications by authors named "Mariia A Bogdanova"
Article Synopsis
- The study examines how the patterns of 5-hydroxymethylcytosine (5hmC) change in human preimplantation embryos during the process of DNA methylation reprogramming.
- It reveals that in zygotes, 5hmC is more concentrated in the paternal chromosome set and is specifically localized to certain regions, known as R-bands, while being sparse in the maternal set.
- As embryonic cleavage occurs, there is a loss of 5hmC and its distribution becomes less symmetrical among sister chromatids, indicating dynamic changes in hydroxymethylation patterns throughout early development.
