Clinical and psychosocial factors associated with the outcome of unipolar major depression: a one year prospective study.

Background: The role of psychosocial and clinical variables in the prediction of major depression is controversial. In a previous paper, we obtained a one-year predictive multivariate model of non-remission for major depression, based on the presence of a personality disorder, a low self-esteem and a low satisfaction with social support.

Objectives: To evaluate more in depth both personality disorders and psychosocial variables as predictors of outcome.