Publications by authors named "Marietya Lauw"
Article Synopsis
- Myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusion (MLN-TK) are rare blood disorders caused by specific gene fusions, and the study investigates treatment outcomes for these conditions using tyrosine kinase inhibitors (TKIs).
- The research included 42 patients, revealing that 60% of those in chronic and blast phases responded positively to upfront TKI therapy, indicating its effectiveness.
- The findings suggest that early initiation of TKI treatment significantly enhances overall survival for patients with MLN-TK, regardless of the specific gene abnormalities involved.
Chromosome rearrangements involving NUP98 at 11p15 are rare but recurring abnormalities in acute myeloid leukemia (AML). Here we described 12 cases of myeloid neoplasms with t(v; 11p15); NUP98 rearrangement and characterized their pathologic features. Our patient cohort included 10 adults and 2 children with a median age of 51 years.
View Article and Find Full Text PDFPrimary central nervous system lymphoma (PCNSL) is a rare form of extranodal non-Hodgkin lymphoma that primarily arises in the brain, spinal cord, leptomeninges, and vitreoretinal compartment of the eye. The term is sometimes used interchangeably with primary central nervous system diffuse large B-cell lymphoma (PCNS DLBCL) because DLBCL comprises a great majority (90-95%) of PCNSL. Although rare, other types of lymphomas can be seen in the central nervous system (CNS), and familiarity with these entities will help their recognition and further workup in order to establish the diagnosis.
View Article and Find Full Text PDFDelayed onset breast implant-associated reactions range widely in symptomatology and underlying etiology. With increasing reports of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), findings such as unilateral breast swelling, capsular thickening, and peri-implant fluid raise concern. Synovial metaplasia is a benign histologic finding commonly associated with implant capsules and can be an unusual cause of such symptoms.
View Article and Find Full Text PDFBackground: Umbilical cord blood (CB) use is limited in most adults since the mean amount of hematopoietic stem cells (HSCs) collected is generally insufficient to engraft successfully. This study demonstrates for the first time the feasibility of pulsatile machine placenta reperfusion (PMPR), which significantly improves CB collection quantity and quality compared to standard collection methods.
Study Design And Methods: PMPR was performed on eight delivered placentas up to 39 hours after venipuncture-based collection.