Publications by authors named "Mariem Mhiri"

Background: Ewing's sarcoma (ES) is a rare malignant tumor primarily affecting young individuals, with cranial localization being particularly uncommon. While intracranial metastatic ES is infrequent, only four cases of intracranial metastatic ES are reported in the literature; it presents unique diagnostic and therapeutic challenges.

Case Description: We present a distinctive case of ES to delineate its clinical, radiological, and histopathological characteristics.

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Background: Hepatic myelopathy is a very rare neurological complication of chronic liver disease. Patients habitually present with progressive pure motor spastic paraparesis. This neurological dysfunction is almost always due to cirrhosis and portocaval shunt, either surgical or spontaneous.

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Background: Behcet's disease (BD) is a multisystem autoimmune relapsing vasculitis with an almost unknown etiology involving both large and small vessels. The neurological involvement called neuro-Behcet's disease (NBD) is rare. NBD can be responsible for tumor-like masses mimicking low-grade gliomas in only a few cases.

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Article Synopsis
  • Multiple sclerosis (MS) is a chronic condition affecting the central nervous system, marked by inflammatory and neurodegenerative processes, with current treatments like natalizumab (NTZ) showing promise but still requiring further evaluation for their impact on neurodegeneration.
  • In a study involving 20 patients with relapsing-remitting MS under NTZ treatment, researchers monitored brain atrophy using MRI, assessing physical disability and cognitive function correlated with changes in brain structure over time.
  • Results showed significant atrophy in specific brain regions early in treatment, linked to memory impairment, but NTZ appeared to not worsen this atrophy and might even have a neuroprotective effect, particularly leading to increased thalamus volume.
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Neurological cytomegalovirus (CMV) infections especially extensive longitudinal myelitis are extremely rare in immunocompetent adults. However, we hereby report a case of cervical, thoracic, and lumbosacral myelitis caused by CMV infection in a healthy adult patient. The patient was treated properly and had a good outcome.

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The rapid spread of the COVID-19 pandemic has raised huge concerns about the prospect of a major health disaster that would result in a huge number of deaths. This anxiety was largely fueled by the fact that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the disease, was so far unknown, and therefore an accurate prediction of the number of deaths was particularly difficult. However, this prediction is of the utmost importance for public health authorities to make the most reliable decisions and establish the necessary precautions to protect people's lives.

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Purpose: Dementia is a multifactorial idiopathic pathology caused by clinical, eDementia is a multifactorial idiopathic pathology caused by clinical, environmental and genetic factors. Hence, its etiology is still unknown. We aimed to evaluate the association between five genetic risk factors for vascular diseases and dementia individually and when gathered in haplotypes.

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