Tumoral inflammatory infiltrate does not predict metastases in thin primary cutaneous melanomas.

Background: In cutaneous melanomas in general, tumor inflammatory infiltrate (TII) can protect against distant metastases, but there is no consensus when only thin primary cutaneous melanomas (TPCM) are considered.

Objective: To investigate the presence of TII in TPCM and the relationship between TII and the occurrence of metastases.

Methods: Case-control study including 50 patients with TPCM, 22 metastatic (MC group) and 28 non-metastatic (NMC group).

Mesalazine in the Treatment of Extensive Alopecia Areata: A New Therapeutic Option?

Background: Alopecia areata (AA) is a T-lymphocyte-mediated disease that results in alopecia plaques or diffuses alopecia on the scalp and body. Etiologic factors include genetic and autoimmune susceptibility. Treatment modalities are usually considered according to the extent of hair loss and the patient's age.