Publications by authors named "Marie-Therese Dangles"

Article Synopsis
  • Water-soluble vitamins are crucial for the nervous system, and their deficiencies can lead to serious, irreversible complications if left untreated; this study aimed to highlight the clinical and laboratory findings related to these deficiencies for better early diagnosis and treatment.* -
  • Between 1998 and 2023, data from patients with neurological symptoms attributed to vitamin deficiencies were analyzed, revealing specific clinical presentations and neuroimaging results for various vitamin deficiencies, such as B1, B2, B12, and C.* -
  • The study concluded that acquired vitamin deficiencies can produce symptoms that resemble inherited metabolic disorders and emphasized the need for prompt diagnosis and treatment to prevent long-term consequences.*
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Periodic discharges are a rare peculiar electroencephalogram pattern, occasionally associated with motor or other clinical manifestations, usually observed in critically ill patients. Their underlying pathophysiology remains poorly understood. Epileptic spasms in clusters and periodic discharges with motor manifestations share similar electroencephalogram pattern and some aetiologies of unfavourable prognosis such as subacute sclerosing panencephalitis or herpes encephalitis.

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Aim: The aim was to describe and to analyze the ethics of decision-making in situations involving children with intellectual disability and cancer, from the referent-doctor's point-of-view, in pediatric oncology units in France.

Methods: Pediatricians working in pediatric oncology units were interviewed through an online questionnaire and a semi-directive interview was systematically proposed. We analyzed the ethical issues that arose during the process of decision-making and we made suggestions in order to address them.

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