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Publications by authors named "Marie-Theres Neumuth"

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Notch3-Dependent Effects on Adult Neurogenesis and Hippocampus-Dependent Learning in a Modified Transgenic Model of CADASIL.
Fanny Ehret Ricardo Moreno Traspas Marie-Theres Neumuth Bianca Hamann Daniela Lasse

Front Aging Neurosci

May 2021

We and others have reported that Notch3 is a regulator of adult hippocampal neurogenesis. (CADASIL), the most common genetic form of vascular dementia, is caused by mutations in . The present study intended to investigate whether there is a correlation between altered adult hippocampal neurogenesis and spatial memory performance in CADASIL transgenic mice.

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Synopsis of recent research by authors named "Marie-Theres Neumuth"

  • Marie-Theres Neumuth focuses on the role of Notch3 in adult neurogenesis and its implications for spatial memory, specifically in relation to CADASIL, a genetic form of vascular dementia.
  • Her research investigates the correlation between altered adult hippocampal neurogenesis and learning performance in modified transgenic models, highlighting the potential impact of Notch3 signaling.
  • The findings contribute to a deeper understanding of the mechanisms underlying neurodegenerative diseases and may inform future therapeutic strategies for cognitive impairments associated with vascular dementia.

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