Publications by authors named "Marie-Pier Thivierge"
Article Synopsis
- * By analyzing blood samples from 118 kidney recipients over a median follow-up of 6.3 years, researchers developed a risk score based on age and immune cell responses, categorizing patients into low, intermediate, and high-risk groups for OIS.
- * The results showed that the risk score accurately reflected the likelihood of OIS events, with significant differences in risk percentages across the categories, highlighting the potential for improved personalized monitoring in organ transplant patients.
Introduction: The process of immunization following vaccination in humans bears similarities to that of immunization with allografts. Whereas vaccination aims to elicit a rapid response, in the transplant recipient, immunosuppressants slow the immunization to alloantigens. The induction of CD4+CXCR5+ T follicular helper (Tfh) cells has been shown to correlate with the success of vaccine immunization.
View Article and Find Full Text PDFSignificance Statement: Donor-specific antibodies against class II HLA are a major cause of chronic kidney graft rejection. Nonetheless, some patients presenting with these antibodies remain in stable histological and clinical condition. This study describes the use of endothelial colony-forming cell lines to test the hypothesis of the heterogeneous expression of HLA molecules on endothelial cells in humans.
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