Identification of furosemide in hair in a post-mortem case by UHPLC-MS/MS with guidance on interpretation.

Testing for drugs in hair raises several difficulties. Among them is the interpretation of the final concentration(s). In a post-mortem case, analyses revealed the presence of furosemide (12 ng/mL) in femoral blood, although it was not part of the victim's treatment.

Development of a new GC-MS/MS method for the determination of metformin in human hair.

Diabetes mellitus is one of the most important public health challenges. Metformin (1,1-dimethylbiguanide) represents the "gold standard" for the treatment of diabetes mellitus type 2. Despite its important role in reducing mortality and morbidity in the diabetic population, metformin is associated with an increased risk of stroke.

[Recognizing patients in life-threatening emergencies or potentially serious conditions].

The identification of a vital distress belongs to necessary knowledge of any medical doctor. The clinical pictures can reach a level of complexity such as the expert is likely to ignore gravity and the immediate attitude to have. However the search for a vital distress starts from an initially simple clinical step and to the range all.