Publications by authors named "Marie-Laurence Poli-Merol"

Introduction: Hypospadias is one of the most common congenital anomalies in men. Outpatient surgery has been proposed but is not widespread. The aim of this study was to evaluate our experience of outpatient surgery for penile hypospadias repair and to specify the constraints for a result similar to a conventional inpatient procedure.

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Background: Large and rapidly growing abdominal tumors may result in fatal outcomes in newborns. In some cases, a rapidly worsening clinical condition requires surgical decision-making despite the absence of a precise histological diagnosis. In these situations, there is neither a guide nor consensus.

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Background: Malignant and multicystic peritoneal mesotheliomas are extremely rare tumors in children, developing from mesothelial cells. No specific guidelines are available at this age.

Methods: We performed a retrospective analysis of all identified children (< 18-year-old) treated in France from 1987 to 2017 for a diffuse malignant peritoneal mesothelioma (DMPM) or a multicystic peritoneal mesothelioma (MCPM).

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Objective: To identify predictors of and factors associated with the performance of antireflux surgery during the first year of life in children born with esophageal atresia.

Study Design: All patients were included in a French registry for esophageal atresia. All 38 multidisciplinary French centers completed questionnaires about perinatal characteristics and one-year outcome for children born with esophageal atresia.

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Article Synopsis
  • * Traditional imaging methods for assessing kidney function and structure are not always effective or quantitative, leading to the exploration of a new MRI technique called intravoxel incoherent motion diffusion for better analysis.
  • * This new method shows promise in evaluating kidney health by measuring perfusion and microstructure without needing contrast agents, suggesting early changes in kidney function linked to reduced blood flow could occur before significant tissue damage.
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Background: Morphometric and anatomical analyses of the shape and position of the umbilicus have been conducted in adults, but umbilicoplasty in children remains challenging because growth is still occurring.

Objectives: The main objective of this study was to evaluate the difference in the position and shape of the umbilicus between childhood and adulthood. The secondary objective was to improve the surgical management of umbilicoplasty in children.

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Article Synopsis
  • The study investigates the use of near infrared spectroscopy (NIRS) to monitor changes in oxygen saturation in the brain and kidneys during neonatal digestive surgeries, emphasizing its importance for adapting resuscitation protocols.
  • It included 19 neonates and found that while cerebral oxygen saturation remained stable, renal oxygen saturation decreased over time, particularly after the first 30 minutes of surgery.
  • The results indicated a significant correlation between renal oxygen saturation and pre-ductal SpO values, but no significant correlations were found with mean arterial pressure, highlighting NIRS's potential as a non-invasive monitoring tool for tissue perfusion in neonates.
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Obstructive nephropathy constitutes a major cause of pediatric renal progressive disease. The mechanisms leading to disease progression are still poorly understood. Kidney fibrotic lesions are reproduced using a model of partial unilateral ureteral obstruction (pUUO) in newborn mice.

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Objective: To assess the objective efficacy of transcutaneous posterior tibial nerve stimulation in children presenting with overactive bladder resistant to well conducted treatment.

Material And Method: This was a randomized, double-blind, controlled study on 20 children with OAB. All patients were previously treated with anticholinergic drugs associated with detrusor rehabilitation, diet advice, bladder-voiding hygiene and constipation treatment, with poor clinical results.

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Familial transmission of chromosome 6 duplications is rare. We report on the first observation of a maternally-inherited pure segmental 6q duplication split into two segments, 6q15q16.3 and 6q16.

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Background: The aim of the present national prospective population-based study was to assess the early morbidity of esophageal atresia (EA).

Methods: All 38 multidisciplinary French centers that care for patients with EA returned a specific questionnaire about the 1-year outcome for each patient. This information was centralized, checked, and entered into a database.

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Introduction: Non-neurogenic detrusor overactivity in children leads to varying degrees of functional impairments (urinary urgency, pollakiuria, urge incontinence, nocturia). Botulinum toxin has shown its effectiveness in the management of detrusor overactivity in neurological patients.

Objectives: To evaluate the relevance of intravesical Botulinum toxin injections for the treatment of non-neurogenic overactive bladders in children.

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We report a family with a rare association of congenital bilateral cataract and cleft palate that has not to our knowledge been previously reported. The lineage has unveiled abnormalities over four generations affecting 21 people with congenital bilateral cataract, with or without cleft palate. The transmission seems autosomal dominant.

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Wandering spleen in children is a rare condition. The diagnosis is difficult, and any delay can cause splenic ischemia. An epidemiologic, semiological, and surgical diagnosis questionnaire on incidence of wandering spleen in children was sent to several French surgical teams.

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A 2.5-year-old boy was referred to the emergency room for a sudden onset of diffuse and increasing abdominal pain with lethargy, abdominal distension, and vomiting, all in the past 24 hours. A plain abdominal X-ray showed gastric distension.

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Ureteric valves are a rare cause of upper urinary tract obstruction. The authors report 3 cases of ureteric valves: one discovered incidentally during assessment of abdominal trauma and two cases detected by antenatal ultrasound. The diagnosis of ureteric valves was suggested by urography in two cases and was confirmed by immediate preoperative retrograde ureteropyelography in all three cases.

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The ureteric multiplicity is a rare malformation with about one hundred cases described in the literature. The rarity of this anomaly and the complexity of possible associated anomalies often make the preoperative diagnosis difficult. The authors report 1 case of partial quadruplicate ureter associated with bladder duplication and 2 cases of triplicate ureter, corresponding to types I, II and III of Smith's classification.

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