Publications by authors named "Marie-Jose Pelinck"
Article Synopsis
- The study aimed to assess the rates of depression, anxiety, and PTSD among women years after experiencing hyperemesis gravidarum (HG) and how these mental health issues relate to the severity of HG symptoms.
- A cohort of 215 women who had been hospitalized for HG provided data through questionnaires measuring anxiety, depression, and PTSD both six weeks and approximately 4.5 years postpartum.
- Results indicated that a significant number of participants experienced elevated levels of anxiety (39.7%) and depression (27.4%) during follow-up, alongside a notable prevalence of PTSD (21.9%), with increased HG severity linked to higher mental health risk scores.
Article Synopsis
- The study explored how the severity of hyperemesis gravidarum (HG) in pregnant women affected cardiometabolic markers in their babies' cord blood.
- It found that lower maternal weight gain was linked to higher levels of glucose and Apo-B in the cord blood, but other measures of HG severity and the use of enteral tube feeding did not show significant associations.
- Overall, while lower weight gain was a notable factor, the study concluded that other HG severity factors and enteral tube feeding did not impact the cardiometabolic markers in the offspring.
Article Synopsis
- Hyperemesis gravidarum (HG) affects 1% of pregnancies and significantly impacts women's quality of life, raising concerns about its long-term effects and recurrence in future pregnancies.
- The study followed 73 women previously hospitalized for HG to measure recurrence rates, instances of postponed or terminated pregnancies due to HG, and identify predictive factors for recurrence.
- Results showed that 89% of subsequent pregnancies experienced HG recurrence, with 40% of women postponing pregnancy plans, and some considering termination due to HG symptoms.
Introduction: Little is known about the pathophysiology of hyperemesis gravidarum (HG). Proposed underlying causes are multifactorial and thyroid function is hypothesized to be causally involved. In this study, we aimed to assess the utility of thyroid-stimulating hormone (TSH) and free thyroxine (FT4) as a marker and predictor for the severity and clinical course of HG.
View Article and Find Full Text PDFStudy Question: Do different oxygen levels during human IVF embryo culture affect embryo utilization, cumulative IVF success rates per cycle and neonatal birthweight?
Summary Answer: After 2 days of culture, a lower oxygen level (5%) leads to more good-quality embryos and more embryos that can be cryopreserved, and thereby to a higher cumulative live birth rate per cycle when compared to embryo culture in 20% oxygen, while birthweights are similar.
What Is Known Already: Several studies have compared IVF outcome parameters after embryo culture in a more physiological level of 5% oxygen and the atmospheric level of 20%. Although there is consensus that embryo development improves in 5% oxygen, effects on pregnancy and live birth rates are mainly seen in blastocyst, but not cleavage-stage transfers.
Determinants of disease course and severity in hyperemesis gravidarum.
Eur J Obstet Gynecol Reprod Biol
February 2020
Objective: We aimed to identify determinants that predict hyperemesis gravidarum (HG) disease course and severity.
Study Design: For this study, we combined data of the Maternal and Offspring outcomes after Treatment of HyperEmesis by Refeeding (MOTHER) randomized controlled trial (RCT) and its associated observational cohort with non-randomised patients. Between October 2013 and March 2016, in 19 hospitals in the Netherlands, women hospitalised for HG were approached for study participation.
Early enteral tube feeding in optimizing treatment of hyperemesis gravidarum: the Maternal and Offspring outcomes after Treatment of HyperEmesis by Refeeding (MOTHER) randomized controlled trial.
Am J Clin Nutr
September 2017
Hyperemesis gravidarum (HG) leads to dehydration, poor nutritional intake, and weight loss. HG has been associated with adverse pregnancy outcomes such as low birth weight. Information about the potential effectiveness of treatments for HG is limited.
View Article and Find Full Text PDFIn vitro fertilisation (IVF) usually involves controlled ovarian stimulation (COS). There is now increasing emphasis on methods that make IVF safer and more patient-friendly. Modified natural cycle (MNC)-IVF is an example of this.
View Article and Find Full Text PDFPerinatal outcome in singletons after modified natural cycle IVF and standard IVF with ovarian stimulation.
Eur J Obstet Gynecol Reprod Biol
January 2010
Objective: Singletons born after IVF treatment are at risk for adverse pregnancy outcome, the cause of which is unknown. The aim of the present study was to investigate the influence of ovarian stimulation on perinatal outcome.
Study Design: In this single-centre retrospective study, perinatal outcome of singleton pregnancies resulting from IVF treatment with (n=106) and without ovarian stimulation (n=84) were compared.
Objective: To study the implantation potential of unselected embryos derived from modified natural cycle IVF according to their morphological characteristics.
Design: Cohort study.
Setting: Academic department of reproductive medicine.