Publications by authors named "Marie-Jeanne Tfd Vrancken Peeters"
Background: Guidelines recommend systemic therapy for stage I HER2+ breast cancer (BC). Neoadjuvant systemic treatment (NAST) allows response-guided adjuvant treatment. However, prior to NAST only clinical nodal staging is available, risking undertreatment if ypN+ is observed.
View Article and Find Full Text PDFAssessing variability in breast cancer management across the world: results of a questionnaire survey amongst global international experts in breast cancer management.
Ecancermedicalscience
September 2022
Background: Breast cancer is the most common cancer in women worldwide with an estimated 2.3 million breast cancer cases diagnosed annually. The outcome of breast cancer management varies widely across the globe which could be due to a multitude of factors.
View Article and Find Full Text PDFArticle Synopsis
- The study analyzed breast cancer characteristics and treatment outcomes in young patients (<40 years) compared to older patients (≥40 years) using data from the NABON Breast Cancer Audit over a nine-year period.
- Young breast cancer patients were found to often present with more aggressive tumor features and tended to receive more neoadjuvant systemic treatments, yet they had similar or better adherence to quality indicators after treatment.
- De-escalation trends in treatment, such as fewer axillary lymph node dissections and a reduction in radiation after surgery, were observed in both age groups, but the omission of radiation post-surgery was noted only in older patients.
Background: This study was designed to explore the feasibility of replacing the conventional peri-/intratumoural ultrasound (US)-guided technetium-99m albumin nanocolloid ((99m)Tc-nanocolloid) administration by an injection of the same tracer guided by a freehand single-photon emission computed tomography (SPECT) device in patients with non-palpable breast cancer with an iodine-125 ((125)I) seed as tumour marker, who are scheduled for a sentinel lymph node biopsy (SLNB). This approach aimed to decrease the workload of the radiology department, avoiding a second US-guided procedure.
Methods: In ten patients, the implanted (125)I seed was primarily localised using freehand SPECT and subsequently verified by conventional US in order to inject the (99m)Tc-nanocolloid.