Publications by authors named "Marie-Eve Roy-Lacroix"
Objective: To summarize the current evidence and to make recommendations for the diagnosis and management of intrahepatic cholestasis of pregnancy.
Target Population: Pregnant people with intrahepatic cholestasis of pregnancy.
Options: Diagnosing the condition using fasting or non-fasting bile acids, classifying disease severity, determining what treatment to offer, establishing how to monitor for antenatal fetal wellbeing, identifying when to perform elective birth.
Background And Objectives: Postpartum anaemia is a prevalent health problem. We aimed to determine the compliance rate for red blood cell (RBC) transfusion indication among postpartum women in a single tertiary care centre in Quebec, Canada.
Materials And Methods: Retrospective cohort study including all women ≥6 h postpartum who received ≥1 RBC transfusion during their delivery hospitalization between January 2005 and February 2022.
Article Synopsis
- A national registry for congenital heart disease (CHD) in Canada aims to streamline research, cut costs, and enhance statistical power by automatically identifying CHD patients from existing clinical data.
- This project successfully extracted data from 885,287 echocardiogram reports and 70,121 clinical records, identifying over 43,000 children and nearly 5,000 fetuses with CHD.
- The initial registry in Québec demonstrates the potential for a centralized, user-friendly database that can support various CHD research projects and potentially expand to a national level.
[Directive clinique n 441 : Surveillance prénatale du bien-être fœtal].
J Obstet Gynaecol Can
September 2023
Objectif: Résumer les données probantes actuelles et formuler des recommandations pour la surveillance prénatale du bien-être fœtal afin de détecter les facteurs de risque périnatal et toute potentielle décompensation fœtale et de permettre une intervention rapide en prévention de la morbidité et la mortalité périnatales.
Population Cible: Personnes enceintes avec ou sans facteurs maternels, fœtaux ou gravidiques associés à des risques périnataux et à la décompensation fœtale.
Options: Utiliser des examens prénataux par technologie de base et/ou avancée en fonction des facteurs de risque de décompensation fœtale.
Article Synopsis
- The objective of the document is to summarize evidence and provide recommendations for antenatal fetal health surveillance (FHS) to identify at-risk pregnancies and allow for timely interventions to reduce perinatal complications.
- It targets pregnant individuals regardless of their risk status and suggests utilizing various antenatal testing methods based on those risks to spot potential fetal decompensation.
- The outcomes aim for early detection to enhance fetal health or prompt delivery; however, while FHS can mitigate adverse situations, its high false-positive rates might lead to unnecessary interventions that could cause harm and increase healthcare costs.
Article Synopsis
- A study analyzed complications during vaginal deliveries comparing passive vs. active second stages in women with medical conditions.* -
- Results showed a higher complication rate in the passive group (50%) compared to the active group (35.4%), and longer labor times in the passive group.* -
- The findings suggest that passive second stage deliveries should be recommended cautiously, only for selected patients.*
Postpartum hypertensive disorders of pregnancy occur in 2-5% of pregnancies. It is a major cause of urgent postpartum consultation and is associated with life-threatening complications. Our objective was to evaluate if local management of postpartum hypertensive disorders of pregnancy was congruent with expert recommendations.
View Article and Find Full Text PDFIncremental Detection of Severe Congenital Heart Disease by Fetal Echocardiography Following a Normal Second Trimester Ultrasound Scan in Québec, Canada.
Circ Cardiovasc Imaging
April 2022
Background: The benefit of fetal echocardiograms (FE) to detect severe congenital heart diseases (SCHD) in the setting of a normal second-trimester ultrasound is unclear. We aimed to assess whether the increase in SCHD detection rates when FE are performed for risk factors in the setting of a normal ultrasound was clinically significant to justify the resources needed.
Methods: This is a multicenter, population-based, retrospective cohort study, including all singleton pregnancies and offspring in Quebec (Canada) between 2007 and 2015.
Background: The effectiveness of screening strategies targeting pregnancies at higher risk of congenital heart disease (CHD) is reduced by the low prevalence of severe CHD, the increase in CHD detection rates by second-trimester ultrasound (U/S), and the high proportion of severe CHD in low-risk pregnancies. We aimed to determine situations in which additional screening by fetal echocardiography (FE) would result in a significant increase in sensitivity and a sizable decrease in the false-negative rate of detection of severe CHD.
Methods: We simulated the change in the numbers of detected severe CHD cases when FE is offered to women with a normal second-trimester U/S who have a higher risk of bearing a child with CHD, compared to U/S alone.
Objective: To evaluate patients' knowledge, risk perception, and anxiety about future health risks after an episode of hypertensive disorder of pregnancy (HDP), as well as their satisfaction with an educational pamphlet.
Methods: From January 2016 to June 2017, participants were randomly assigned to one of 2 groups and asked to complete questionnaire #1 (demographics, knowledge, risk perception, anxiety, and satisfaction) after receiving medical counselling at the HDP postpartum clinic. Participants in the intervention group then received the educational pamphlet.
Objective: Prenatal detection of congenital heart diseases (CHD) decreases morbidity and cost. To improve detections rates, most physicians refer pregnant women with high-risk pregnancies to fetal cardiologists even when there is no suspicion of CHD at the second trimester screening. This paper presents the rationale and detailed method of the Fetal Cardiac Registry of Québec to Improve Resource Utilization in Fetal Cardiology (FREQUENCY) study.
View Article and Find Full Text PDFObjectives: To evaluate the in vitro effect of tamsulosin and nifedipine on the contractility of pregnant rat ureters and to perform quantitative analysis of the pharmacological effects. Medical expulsive therapy (MET) is commonly used to treat urolithiasis. However, this treatment is seldom used in pregnant women since no studies support this practice.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to evaluate how long fetal exposure to inflammation affects the neurological development of newborn rats after being exposed to lipopolysaccharides (LPS).
- - Researchers injected pregnant rats with LPS at various times before delivery and found that longer exposure led to increased mortality and lower motor activity in the pups, particularly in those exposed for 12 hours.
- - The findings suggest that there is a critical time limit for preventing brain damage due to inflammation during pregnancy, indicating the need for timely deliveries in such cases.