Publications by authors named "Marie-Celine Blanc-Quintin"
Article Synopsis
- - The practice of measuring cerebrospinal fluid (CSF) biomarkers for diagnosing Alzheimer's disease (AD) is inconsistent across different medical centers, leading to varied interpretations of the same results.
- - A study involving 40 centers worldwide analyzed their analytical protocols and reports to create a consensus on how to interpret CSF biomarker profiles effectively.
- - The findings highlighted that while the analytical methods were largely similar, there was significant variability in how results were reported; as a result, harmonized reporting formats were established for clearer communication among laboratories.
Background & Aims: Excess weight and type 2 diabetes lead to increased susceptibility to infections. Our aim was to investigate the role of diabetes-induced decreased arginine (Arg) availability and of a possible dysregulation of Arg metabolism in macrophages favoring inflammation and dysimmunity via altered nitric oxide (NO) and cytokine productions.
Methods: Isolated peritoneal macrophages from Zucker Diabetic Fatty (ZDF) or lean rats were incubated with increasing Arg concentration (0-2 mM) and Arg metabolism and regulatory properties were studied.