Impact of iron sucrose therapy on leucocyte surface molecules and reactive oxygen species in haemodialysis patients.

Background: It has been suggested that iron increases oxidative stress and that an excess of iron contributes to cardiovascular disease and infections in haemodialysis patients. In the present study, the effects of parenterally administered iron on leucocyte surface molecule expression and the production of reactive oxygen species (ROS) were evaluated.

Methods: Ten chronic haemodialysis (HD) patients without iron overload were studied.