Assessment of different intervention models to decrease no-show rates of embedded pharmacy visits.

Background: Clinical pharmacist practitioners (CPPs) are embedded in several Duke Primary Care (DPC) clinic locations. CPPs are able to independently modify medications and order labs within protocol in collaboration with a supervising physician. Patient no-shows for CPP appointments are costly to clinics.

Maternal Vascular Lesions in the Placenta Predict Vascular Impairments a Decade After Delivery.

Women with adverse pregnancy outcomes later experience excess hypertension and cardiovascular disease, but how the events are linked is unknown. Examination of the placenta may provide clues to vascular impairments after delivery. Maternal vascular malperfusion lesions (MVMs) were abstracted from clinical reports, validated and characterized using clinical guidelines and severity score.

Spectra in low-rank localized layers (SpeLLL) for interpretable time-frequency analysis.

The time-varying frequency characteristics of many biomedical time series contain important scientific information. However, the high-dimensional nature of the time-varying power spectrum as a surface in time and frequency limits its direct use by applied researchers and clinicians for elucidating complex mechanisms. In this article, we introduce a new approach to time-frequency analysis that decomposes the time-varying power spectrum in to orthogonal rank-one layers in time and frequency to provide a parsimonious representation that illustrates relationships between power at different times and frequencies.

Dynamic changes in the pancreatitis activity scoring system during hospital course in a multicenter, prospective cohort.

Background And Aim: The primary aim was to validate the Pancreatitis Activity Scoring System (PASS) in a multicenter prospectively ascertained acute pancreatitis (AP) cohort. Second, we investigated the association of early PASS trajectories with disease severity and length of hospital stay (LOS).

Methods: Data were prospectively collected through the APPRENTICE consortium (2015-2018).

Association of Serum Triglyceride Levels with Severity in Acute Pancreatitis: Results from an International, Multicenter Cohort Study.

Background: Hypertriglyceridemia (HTG) is considered within the top 5 etiologies in acute pancreatitis (AP), but the association of serum triglyceride (TG) levels with the clinical course of AP remains controversial.

Objectives: This study aims to examine the effect of TG levels on severity of AP.

Methods: Patients were enrolled prospectively through APPRENTICE.

Access to Lung Transplantation in the United States: The Potential Impact of Access to a High-volume Center.

Background: Health disparities plague our healthcare system. Utilizing a novel approach, we sought to assess the effects of geographic disparities on access to lung transplantation (LT) in the United States.

Methods: A total of 13 743 LT adult recipients in the United Network for Organ Sharing Database were identified between May 2005 and December 2014 with a zip code status.

The use of pancreatic enzyme replacement therapy in patients with a diagnosis of chronic pancreatitis and pancreatic cancer in the US is infrequent and inconsistent.

Background: Patients with chronic pancreatitis or pancreatic cancer commonly develop exocrine pancreatic insufficiency, and may not be adequately treated with pancreatic enzyme replacement therapy (PERT).

Aims: To estimate the frequency of diagnostic testing for exocrine insufficiency, and appropriate use of PERT, in a commercially insured population in the US.

Methods: We utilised a nationally representative administrative database representing 48.

Clinical features of hypertriglyceridemia-induced acute pancreatitis in an international, multicenter, prospective cohort (APPRENTICE consortium).

Background: The clinical features and outcomes of hypertriglyceridemia-induced acute pancreatitis (HTG-AP) are not well-established.

Objective: To evaluate the clinical characteristics of HTG-AP in an international, multicenter prospective cohort.

Methods: Data collection was conducted prospectively through APPRENTICE between 2015 and 2018.

Routine deep vein thrombosis screening after lung transplantation: Incidence and risk factors.

Background: Deep vein thrombosis (DVT) remains a common complication following lung transplantation despite universal routine DVT screening. Moreover, many of the previously reported risk factors are incompletely defined. We sought to explore the influence of DVT screening and to more definitively assess predisposing risk factors.

Etiology and treatment outcomes of persistent postoperative inflammation in primary resident-performed cataract surgeries at a large tertiary care public hospital.

Purpose: To determine the risk factors, intraoperative and postoperative complications, therapeutic interventions, and visual outcomes for persistent postoperative inflammation in primary resident-performed cataract surgeries.

Setting: Ben Taub General Hospital, Houston, Texas, USA.

Design: Retrospective case series.

Patent foramen ovale repair at the time of double lung transplantation: Necessary or not?

Introduction: Patient foramen ovale (PFO) is a common and often incidental intraoperative finding during lung transplantation (LTx). We sought to characterize the potential outcomes related to the decision making of whether the PFO was repaired or left unrepaired.

Methods: We retrospectively evaluated bilateral LTx recipients between 2005 and 2015 from our prospective database.

Coarse-graining intermittent intracellular transport: Two- and three-dimensional models.

Viruses and other cellular cargo that lack locomotion must rely on diffusion and cellular transport systems to navigate through a biological cell. Indeed, advances in single particle tracking have revealed that viral motion alternates between (a) diffusion in the cytoplasm and (b) active transport along microtubules. This intermittency makes quantitative analysis of trajectories difficult.