Publications by authors named "Marie Thiele"

Moisture-responsive materials are gaining greater interest for their potentially wide applications and the readily access to moisture. In this study, we show the fabrication of moisture-responsive, self-standing films using sustainable cellulose as starting material. Cellulose was modified by stearoyl moieties at first, leading to cellulose stearoyl esters (CSEs) with diverse degrees of substitution (DSs).

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The prostate adenocarcinoma is the cancer with the highest incidence for men in Western countries. Targeting the androgen receptor (AR) by antagonists is used as hormone therapy for prostate cancer (PCa), however, eventually therapy resistance occurs in most patients. In most of these cancer the AR signaling is active and thus AR remains an important drug target.

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Androgen receptor (AR) antagonists are important compounds for the treatment of prostate cancer (PCa). The atraric acid (AA), a natural compound, binds to the AR and acts as a specific AR antagonist. Interestingly, AA represents a novel chemical platform that could serve as a potential basis for new AR antagonists.

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