Publications by authors named "Marie Storebjerg Gissel"

Objective: To describe the associations among preoperative characteristics, intraoperative and postoperative factors, and mortality and morbidity after open-heart surgery in patients age ≥80 years.

Methods: This retrospective multicenter register study was based on prospectively collected data of all patients age ≥80 years undergoing open-heart surgery in western Denmark between 1999 and 2016. Logistic regression was used to estimate the associations among preoperative characteristics, intraoperative and postoperative factors, and morbidity and mortality.

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Article Synopsis
  • This study examines the impact of discontinuing the antiplatelet drug ticagrelor before cardiac surgery to reduce the risk of major bleeding complications.
  • It involved analyzing data from 3,377 patients, comparing those who took ticagrelor with those who only took aspirin prior to surgery.
  • Findings indicated that stopping ticagrelor 0-72 hours before surgery significantly increased the risk of major bleeding, while discontinuation 72-120 hours before was not linked to a higher risk.
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Introduction: A clear advantage of blood versus crystalloid cardioplegia has not yet been observed in smaller population studies. The purpose of this article was to further investigate the clinical outcomes of blood versus crystalloid cardioplegia in a large propensity-matched cohort of patients who underwent cardiac surgery.

Methods: The study was a single-centre study.

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Objective: The right choice of fluid replacement still is a matter of debate. Recently, two large-scale studies on the use of hydroxyethyl starches (HES) in the intensive care setting have been published, which have caused a huge shift in the daily practice of volume therapy. These results have been applied to patients outside intensive care.

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