Clinical course, risk factors, and treatment of microcystic adnexal carcinoma: a short series report.

Background: Microcystic adnexal carcinoma (MAC) is a locally aggressive neoplasm of both eccrine and follicular differentiation; it commonly presents on the head and neck of white middle-aged to older patients.

Objective: To review the course, risk factors, and management of 10 patients with microcystic adnexal carcinoma (MAC) and to compare treatment outcome by either Mohs micrographic surgery or standard surgical excision.

Methods: Tumor registry databases were used to identify cases at Roswell Park Cancer Institute in Buffalo, New York.