Publications by authors named "Marie Sevcikova"

Objectives: The aim of this study was to assess the impact of ciprofloxacin in Danio rerio on growth, on the development of histopathological changes in selected organs (gills, kidney, liver), and on the activity of some oxidative stress markers during a 28-day toxicity test.

Methods: Juvenile growth tests were performed on D. rerio according to OECD guideline No.

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The effects of Nexide (a.i. gamma-cyhalothrin 60 g L(-1)) on cumulative mortality, growth indices, and ontogenetic development of embryos and larvae of common carp (Cyprinus carpio L.

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The aim of study was to evaluate the effect of atrazine exposure (5, 15, 20, and 30 mg·L(-1)) on common carp and the ability of regeneration. During 96 h exposure we observed abnormal behavior in fish exposed to 20 and 30 mg·L(-1). Mortality and histological alterations were noticed only in the group exposed to 30 mg·L(-1).

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Deoxynivalenol (DON), produced by the Fusarium genus, is a major contaminant of cereal grains used in the production of fish feed. The effect of mycotoxin deoxynivalenol on rainbow trout (Oncorhynchus mykiss) was studied using a commercial feed with the addition of DON in a dose of 2 mg/kg feed. The fish (n=40) were exposed to the mycotoxin for 23 days.

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Article Synopsis
  • This study aimed to assess how juvenile zebrafish respond to prolonged exposure to acetylsalicylic acid using oxidative stress biomarkers over a 28-day period.
  • Results showed that specific antioxidant enzyme activities, such as glutathione S-transferase and catalase, significantly increased in fish exposed to certain concentrations of acetylsalicylic acid, indicating a protective response against oxidative stress.
  • Overall, exposure to acetylsalicylic acid led to enhanced antioxidant enzyme activity and reduced lipid peroxidation, suggesting a potential adaptive mechanism in zebrafish to counteract toxin effects.
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Objectives: The objective of the presented study was to investigate levels of the most important biochemical markers in fish which were caught upstream and downstream from sites near waste water treatment plants situated at 3 selected small streams of the Czech Republic. Organic pollutants and mercury were determined in muscle tissue of fish for complex assessment.

Design: Levels of biochemical markers (cytochrome P450 (CYP450), ethoxyresorufin-O-deethylase (EROD), glutathione S-transferase (GST), vitellogenin (VTG)) were measured in selected tissues (liver, plasma, brain, gill and kidney) samples of brown trout.

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Objectives: Thiomersal is ethylmercury containing compound. It has been used as a preservative in vaccines since the 1930s because it is very effective in preventing bacterial contamination. Ethylmercury penetrates into growing hair in a similar manner as methylmercury.

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Objectives: The aim of this study was to compare the acute toxicity of acetylsalicylic acid to embryonic and juvenile stages of aquarium fish - zebrafish (Danio rerio), oxidative stress parameters and detoxifying enzyme.

Methods: Tests were performed according to OECD No. 203 (Fish, acute toxicity test) and OECD No.

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