The study aimed to determine if opioid-free anesthesia (OFA) could reduce postoperative opioid use during laparoscopic colectomy compared to opioid-sparing anesthesia (OSA).
In a clinical trial with 160 patients, those receiving OFA did not show significantly lower opioid consumption 48 hours post-surgery compared to those on OSA.
Both anesthesia methods resulted in similar pain control and adverse events, although the OFA group experienced increased bradycardia incidents.