Publications by authors named "Marie Penoty"
Background: Gastrostomy is recommended in patients with Amyotrophic Lateral Sclerosis (ALS) in the presence of weight loss over 10% as compared to usual weight, repeated aspirations or meal time duration longer than 45 min. Currently, the impact of gastrostomy on survival of ALS patients is not clear.
Aims: i) to describe diagnosis factors associated with the indication for gastrostomy ii) to evaluate survival of ALS patients with gastrostomy indication according to their acceptance of feeding tube placement.
Clinical features and prognosis of amyotrophic lateral sclerosis in Africa: the TROPALS study.
J Neurol Neurosurg Psychiatry
January 2019
Article Synopsis
- The study investigates ALS (amyotrophic lateral sclerosis) patients in Africa, highlighting sociodemographic and clinical features, treatments, and survival patterns.
- Out of 185 patients diagnosed between 2005 and 2017, there was a male predominance and a median age of onset at 53.0 years, with a significantly lower use of the drug riluzole compared to Western nations.
- The median survival time was 14.0 months, with Northern Africa showing better survival rates than Western and Southern Africa, indicating that location and treatment affect longevity in ALS patients.