Publications by authors named "Marie N Lavaut"
Article Synopsis
- Phage display is a method to find binders for various antigens, which can be tested both on purified proteins and whole cells, but its efficiency can be inconsistent due to challenges in selection steps.* -
- A new technique called masked selection improves the process by blocking unwanted binding sites, allowing researchers to focus on relevant targets, demonstrated by successfully isolating antibodies against certain proteins and cancer markers.* -
- This approach was validated by identifying specific breast cancer markers and can be utilized for diverse types of antibody fragments, making it beneficial for swiftly discovering important cell surface markers.*
The immunocytochemical detection of Tie-2/Tek, CD105, and CD31 was assessed in a large series (n = 905) of breast carcinomas on frozen sections. Results were correlated with patients' long-term outcome (median, 11.7 years) to define the respective prognostic significance of these markers.
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