Feasibility of advanced composite endpoint analysis: Post-hoc insights from the vitamin intervention for stroke prevention randomized control trial.

Background And Aims: Stroke is a major cause of mortality and disability, highlighting the importance of prevention. Clinical trials play an important role in evaluating interventions that can maximize stroke prevention. Traditional composite endpoints (TCE) used in clinical trials have limitations, as they pool together events of varying clinical importance.

Clinical experience and categorical perception of children's speech.

Background: Accurate and detailed records of children's speech are a critical component of competent service delivery in speech-language pathology/speech and language therapy (SLP/SLT). Previous research has shown that during speech-sound acquisition, children gradually learn to produce sounds in adult-like manners. Continuous rating scales are a way to track this gradual learning.

Deconstructing phonetic transcription: covert contrast, perceptual bias, and an extraterrestrial view of Vox Humana.

This article honours Adele Miccio's life work by reflecting on the utility of phonetic transcription. The first section reviews the literature on cases where children whose speech appears to neutralize a contrast in the adult language are found on closer examination to produce a contrast (covert contrast). This study presents evidence from a new series of perception studies that covert contrast may be far more prevalent in children's speech than existing studies would suggest.