A case study discusses a 32-year-old man with weakened immunity due to kidney transplants, who had a prolonged positive test for SARS-CoV-2.
Genome sequencing of samples taken 12 days apart identified the BA.1.1 Omicron variant and showed viral mutations changing over time.
The report stresses the importance of ongoing monitoring for immunocompromised individuals, as they could contribute to the emergence of new viral strains that might evade immune responses.
Background: Following the emergence of the JN.1 SARS-CoV-2 variant, variants with key mutations in the spike protein, such as L455F, F456L, and R346T, were identified. In early January 2024, the KP.