Preclinical evaluation of [F]FDG-PET as a biomarker of lymphoid tissue disease and inflammation in Zika virus infection.

Purpose: Zika (ZIKV) is a viral inflammatory disease affecting adults, children, and developing fetuses. It is endemic to tropical and sub-tropical countries, resulting in half the global population at risk of infection. Despite this, there are no approved therapies or vaccines against ZIKV disease.