Publications by authors named "Marie Gabrielle Guedat"

Objective: To assess the impact of investigational drug labels on the risk of medication error in drug dispensing.

Design: A simulation-based learning program focusing on investigational drug dispensing was conducted.

Setting: The study was undertaken in an Investigational Drugs Dispensing Unit of a University Hospital of Lyon, France.

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Background: To reduce the occurrence of medication errors, a systemic approach was developed combining anti-neoplastic medication error reviews and morbidity and mortality conferences (M&MCs). We report the first experience of implementing this strategy in oncology.

Methods: The case reports submitted to combined reviews were prepared by physicians and pharmacists, and medication error(s) were described and chronological and root-cause analyses were performed.

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Background: Even though anticancer drugs are prepared in dedicated pharmaceutical units, nurses remain exposed to cytotoxic agents during administration to patients.

Objective: The aim of this study was to assess this occupational exposure during the intravenous line-purging procedure at the patient's bedside before administration in oncology departments.

Methods: This prospective study was conducted over a 4-week period in the hematology and oncology departments at a university hospital.

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Background: Oxaliplatin-based regimens induce a potential risk of hypersensitivity reaction (HSR), with incidence varying from 10% to 25% and lack of clearly identified risk factors. The present study aimed to assess incidence and risk factors in HSR.

Methods: All patients treated with oxaliplatin in the Medical Oncology Department of the Lyon Sud University Hospital (Hospices Civils de Lyon, France) from October 2004 to January 2011 were enrolled.

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Introduction: Underreporting is the main limit in any pharmacovigilance system relying on spontaneous notification. Available data emphasize that pharmacists report few adverse drug reactions (ADRs) in France.

Objective: To report how the integration of pharmacists in health care units contributes to reporting of ADRs and to study the validity of the reports.

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