Publications by authors named "Marie E Brake"

Type of feed is an important consideration in herbivore colony management, yet limited studies report on the effects of diet on common conditions such as urolithiasis in guinea pigs. Urolithiasis is a well-documented cause of lower urinary tract disease in guinea pigs, with calcium carbonate uroliths reported as the predominant calculi formed in the guinea pig urinary tract. A calcium-rich diet has been suggested as a risk factor for of urolithiasis, with numerous commercially available guinea pig diets formulated for adults avoiding ingredients that are higher in calcium.

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Article Synopsis
  • Mice are commonly used in influenza research because they are easy to handle and show clear signs of infection, but analgesia is often avoided in studies due to potential impact on the results.
  • There is a concern that using pain relief medications could confound primary study outcomes like infection progression and immune response.
  • This study found that administering extended-release buprenorphine for pain relief in mice did not affect their clinical signs, mortality, or antibody responses, suggesting it can be safely used for animal welfare without impacting research results.
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