MUC-1 expression in pleomorphic adenomas using two human milk fat globule protein membrane antibodies (HMFG-1 and HMFG-2).

Unlabelled: Pleomorphic adenoma (PA) is the most common salivary gland tumor and its microscopic features and histogenesis are a matter of debate. Human milk fat globule protein membrane (HMFG) monoclonal antibodies (MoAbs) comprise a set of antibodies against the mucin 1 (MUC-1) protein detected in several salivary gland tumors.

Objective: The aim of this study was to assess the immunoexpression of the PA neoplastic cells to MUC-1 protein using HMFG-1 and HMFG-2 MoAbs, contrasting these results with those from normal salivary gland tissue.

Scanning Electron Microscopic Study on the Fibrillar Structures within Dentinal Tubules of Human Dentin.

Introduction: Pulp biology is central to the whole tooth, and knowledge on its microstructure is changing with new studies. This study presents certain microfibrillar structures found within the dentin tubules of human teeth connecting dentin tubules and odontoblastic processes.

Methods: We analyzed the crowns of 30 noncarious, human teeth.

Toxicity test of a dental commercial composite.

Background: International rules must be followed for testing biosecurity in dental materials. A new brand of restorative material appeared in the market and regulations indicated that it should be tested for toxicity.

Objectives: The aim of this study was to determine the 90-day sub chronic toxicity of one triethylene glycol dimethacrylate containing composite (MEDENTAL Light-Cure Composite™) orally administered to rats according to Organization for Economic Co-Operation and Development no.

Review of the literature on necrotizing sialometaplasia and case presentation.

The aim of this article is to report a case of necrotizing sialometaplasia with long-term follow-up. A case of necrotizing sialometaplasia in a 37-year-old man with clinical documentation on the progress during a 2-year follow-up is presented. Data from an extensive review of the literature including clinical, imagenologic, and microscopic features are provided.

Presence of matrix vesicles in the body of odontoblasts and in the inner third of dentinal tissue: a scanning electron microscopic study.

Objectives: The aim of this report is to present the results of a scanning electron microscopic study on the presence of matrix vesicles (MVs) found in human dentine.

Study Design: Dentin tissue from 20 human bicuspids was analyzed by means of scanning electron microscopy.

Results: MVs were found as outgrowths of the cellular membrane of the odontoblastic body, the more proximal portion of the odontoblastic process before entering the dentinal tubule and in the odontoblastic process within the inner third of the dentin.

Multiple supernumeraries in a non-syndromic patient.

Presence of supernumerary teeth (ST) in non-syndromic patients is an exceptional event. The aim of this article is to present an unusual case of a non-syndromic 12 years old girl with 12 ST In the reported case supernumeraries were found in three quadrants and the most common ST were bicuspids. All ST were surgically excised and occlusion and functionality was restored with prosthetic appliances.

Scanning electron micrographic features of a giant submandibular sialolith.

To recognize recently appearing mineralization phenomena, one must study the external surface of the sialoliths, since it is not possible to study them in the central portions of sialoliths. The authors examined the external surface of a sialolith by scanning electron microscopy and analyzed its microstructures. The study revealed the presence of numerous microstructures of different shapes (nodular, laminar, reticular, microgranular, and multinodular) and variable size arranged in a haphazard fashion.

Clinicopathological and immunocytochemical study of multifocal epithelial hyperplasia.

Purpose: We present the clinicopathological findings after reviewing 52 patients affected by multifocal epithelial hyperplasia (MEH), previously known as focal epithelial hyperplasia and the results of an immunocytochemical study.

Patients And Methods: We reviewed the clinical files and microscopic slides from 52 MEH-affected patients and new slides were immunostained with a polyclonal antibody against high molecular weight cytokeratins.

Results: More than 95% of the patients were in poverty (<200 dollars monthly family income).

Immunoexpression of the HLA-DR class II molecule in cells from inflamed dental pulp.

Background: Despite that the role of inflammatory cells in chronic inflammatory reactions of pulpal origin (CIRPOs) has been extensively studied, function of the HLA-DR+ cells (HLA-DR+ Cs) is poorly understood. The aim of this study was to quantify their number and clarify their role in these lesions.

Methods: We studied 11 CIRPOs immunostained with an anti-HLA-DR class II monoclonal antibody and the number and location of the HLA-DR+ Cs quantified.

Multifocal epithelial hyperplasia. Report of nine cases.

Multifocal epithelial hyperplasia (MEH) is also known as focal epithelial hyperplasia, Heck's disease or multifocal papillomavirus-induced epithelial hyperplasia. It is characterised by the presence of multiple lesions in the oral mucosa of children and it has been associated with the presence of the human papillomavirus. The aim of this study was to determine the clinico-pathological features of the cases diagnosed as MEH in the Service of Dermatology of the Hospital Manuel Gea González (SDHMGG).

Frequency of supernumerary teeth in Mexican population.

Supernumerary teeth (ST) are a not uncommon developmental anomaly which appears in 0.3 to 3.8 percent of the population.

Importance of mast cells in human periapical inflammatory lesions.

The role of mast cells (MCs) in periapical inflammatory lesions is not well understood. The objective of this work was to quantify MC numbers in human periapical lesions with the aim to clarify their role in the pathogenesis of these lesions. We analyzed the slides of 64 human periapical inflammatory lesions stained with pH 8.