Publications by authors named "Maribel G Martinez Wassaf"

Article Synopsis
  • In Argentina, hepatitis E virus (HEV) genotype 3 has been found in sporadic cases of acute and chronic hepatitis, but there's limited data on its effects in children.
  • A study analyzed serum samples from 213 children aged 0-18, with low seropositivity for IgG anti-HEV at just 1.49%.
  • One 18-year-old patient with acute hepatitis showed positive results for IgM anti-HEV, but also tested positive for IgM anti-EBV, indicating some awareness of viral infections in this age group.
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Background: The hepatitis E virus (HEV) causes acute hepatitis, which can progress to chronicity in immunosuppressed patients. It is transmitted mainly by the fecal-oral or zoonotic routes, but there is current evidence that it can be transmitted by blood transfusions. The objective of the study was to investigate HEV infections in blood donors in Argentina, within the framework of a hemovigilance program.

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Background: Few studies about the evolutionary history of the hepatitis E virus (HEV) have been conducted. The aim of our work was to investigate and make inferences about the origin and routes of dispersion of HEV-3 in Argentina.

Methods: Phylogenetic, coalescent and phylogeographic analyses were performed using a 322-bp ORF2 genomic fragment of all HEV-3 sequences with known date and place of isolation published at GenBank until May 2018 (n=926), including 16 Argentinian sequences (isolated from pigs, water and humans).

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Background: Hepatitis E virus (HEV) infection is an important cause of acute hepatitis worldwide. In pregnant women, HEV can cause more severe symptoms, with high rates of fatal hepatic failure in endemic countries. However, HEV prevalence and circulation among pregnant women from South America is almost unknown.

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Introduction: Little is known about hepatitis E virus (HEV) infection in patients with cirrhosis. The aim of the present study was to describe the frequency of HEV infection and associated risk factors in patients with cirrhosis from Argentina.

Materials And Methods: We evaluated HEV seroprevalence (IgG anti-HEV) and acute infections (IgM and RNA) in patients with cirrhosis (n = 140) vs.

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Background: The hepatitis E virus (HEV) causes hepatitis worldwide. In Europe, wild boars are known to be viral reservoirs and sources of infection. In South America, there is a lack of information about HEV in these animals.

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Background: Hepatitis E virus (HEV) is an emergent cause of acute hepatitis worldwide. Water contamination is a possible source of viral infection. In South America, particularly in Argentina, little is known about environmental HEV circulation, including recreational water.

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Hepatitis E virus (HEV) is one of the most frequent causes of acute viral hepatitis of enteric transmission worldwide. In South America the overall epidemiology has been little studied, and the burden of the disease remains largely unknown. A research of all scientific articles about HEV circulation in South America until November 2017 was carried out.

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Article Synopsis
  • * The study conducted environmental surveillance on river and sewage samples and a serological survey on healthy adults, finding HEV in 6.3% of sewage and 3.2% of river samples, with a 4.4% prevalence of anti-HEV IgG in serum samples.
  • * Results indicate that HEV circulates locally, especially in water sources, highlighting the need for improved detection in local health systems to prevent potential outbreaks in susceptible populations.
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