Pharmaceuticals can exist in many solid forms, which can have different physical and chemical properties. These solid forms include polymorphs, solvates, amorphous, and hydrates. Particularly, hydration process can be quite common since pharmaceutical solids can be in contact with water during manufacturing process and can also be exposed to water during storage.
View Article and Find Full Text PDFThe present 0.25-hydrated form of rosiglitazone maleate [systematic name: (+/-)-2-({2-[2,4-dioxo-1,3-thiazolidin-5-ylmethyl)phenoxy]ethyl}methylamino)pyridinium maleate 0.25-hydrate], C(18)H(20)N(3)O(3)S(+) x C(4)H(3)O(4)(-) x 0.
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