Publications by authors named "Mariastella Graziani"
Article Synopsis
- The study aimed to determine the incidence and predictors of contrast-induced nephropathy in patients undergoing coronary procedures, evaluating renal function at 30 days post-exposure.
- 216 patients were monitored at multiple time points after contrast media exposure, with 18% experiencing nephropathy and 7% showing renal damage at 30 days.
- Early changes in serum creatinine levels (especially 12 hours after exposure) were found to be strong indicators of both immediate contrast-induced nephropathy and subsequent renal impairment, suggesting careful monitoring in at-risk patients.
The detection and quantification of monoclonal free light chains in urine (Bence Jones protein, BJP) are thorny issues for the laboratorian. Immunoelectrophoretic techniques (immunofixation) allow the characterization of the two pathognomonic features of light chains: monoclonality and absence of heavy chains. Immunochemical methods such as nephelometry and turbidimetry are widely used in clinical practice to exclude the presence of BJP.
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