Publications by authors named "Mariasole Colombo"

Toxoplasmosis caused by Toxoplasma gondii is a protozoal zoonosis with high sanitary risk for pregnant women and immunocompromised people. Felids, including domestic cats, are the only definitive hosts of T. gondii.

View Article and Find Full Text PDF
Article Synopsis
  • The tapeworm Dipylidium caninum is a common parasite in dogs, cats, and humans, with diagnosis typically relying on observing segments in feces or using microscopy, both of which may miss infections.
  • A study was conducted on 100 cats in Italy and Greece, comparing various sampling methods (feces, Scotch tape test, and rectal swab) to test for D. caninum using PCR, which is a more sensitive detection method.
  • Results indicated that while PCR could effectively identify D. caninum in certain samples, it also faced challenges like false negatives and variability in parasite distribution, highlighting its potential as a diagnostic tool under specific conditions.
View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the effectiveness of a spot-on treatment called NexGard® Combo, containing eprinomectin, esafoxolaner, and praziquantel, for treating respiratory diseases in cats caused by metastrongyloids Aelurostrongylus abstrusus and Troglostrongylus brevior.
  • Conducted with 36 infected cats divided into two groups, the treatment regimen involved administering the medication on specified study days while monitoring parasitological, clinical, and radiographic changes.
  • Results showed 100% efficacy in reducing larval shedding in cats with single infections and significant clinical improvement in all cats after two treatments, highlighting the treatment's effectiveness against the parasites.
View Article and Find Full Text PDF
Article Synopsis
  • Heartworm disease in dogs, caused by the parasite Dirofilaria immitis, is hard to treat but easy to prevent with medications called macrocyclic lactones (MLs).
  • A recent case in Rome described a dog that tested positive for heartworms after arriving from the USA, despite treatment with MLs, indicating the presence of a resistant strain.
  • Genetic analysis confirmed the dog's infection was caused by a ML-resistant strain, raising concerns about the risk of such strains spreading into Europe and underscoring the need for monitoring dogs from regions known for ML-resistance.
View Article and Find Full Text PDF

This clinical study assessed the efficacy of a topical combination of esafoxolaner, eprinomectin and praziquantel (NexGard Combo) in treating cats naturally infected with the eyeworm Thelazia callipaeda (Nematoda, Thelaziidae). On Study Day (SD) 0, sixteen client-owned cats with eyeworm infection were allocated to an untreated control group (G1, 8 cats) or to a NexGard Combo treated group (G2, 8 cats) and subjected to ocular examination. Cats in G2 received the treatment as per label recommendations.

View Article and Find Full Text PDF

Feline pulmonary capillariosis is a significant disorder due to its distribution and clinical impact. This study evaluated the safety and efficacy of two administrations 28 days apart of a topical solution containing esafoxolaner, eprinomectin and praziquantel (NexGard Combo) in treating Eucoleus aerophilus (syn. Capillaria aerophila) infection in naturally infected cats.

View Article and Find Full Text PDF

Aelurostrongylus abstrusus is the most important respiratory nematode of domestic cats. Effective control options are crucial to protect health and welfare of cats and to reduce the spread of aelurostrongylosis in both enzootic and free regions. The present study evaluated the efficacy of a spot-on formulation containing 280 mg/ml fluralaner and 14 mg/ml moxidectin (Bravecto® Plus, MSD) in the prevention of aelurostrongylosis in cats under field conditions.

View Article and Find Full Text PDF

Parasitic diseases caused by uncommonly diagnosed parasites may pose a threat to companion animals' health in urban environments where they are least expected. The pentastomid Linguatula serrata (tongue worm) and the capillarid Pearsonema plica (syn. Capillaria plica) are parasites with an indirect life cycle, infecting both domestic and wild carnivores.

View Article and Find Full Text PDF
Article Synopsis
  • - Canine Vector-Borne Diseases (CVBDs) are common in Europe, with many dogs showing no symptoms, making undiagnosed infections a risk for spreading diseases to other animals and potentially humans.
  • - A study tested 300 privately owned dogs in Italy and Greece for CVBD exposure using rapid diagnostic kits, revealing that 17% were positive for at least one disease, with significantly higher rates in Greece (31.3%) than in Italy (2.7%).
  • - The study highlights the effectiveness of in-clinic diagnostic kits in detecting CVBDs quickly and cost-effectively, even when dogs display no clinical signs, underscoring the importance of regular screenings in enzootic regions.
View Article and Find Full Text PDF

Equine and canine anaplasmosis and borreliosis are major tick-borne zoonotic diseases caused by and various species of (the most important being s.l.), respectively.

View Article and Find Full Text PDF

The burrowing mite causes sarcoptic mange in dogs and other mammals, including humans. Despite infests several animals, little is known about the epidemiology, clinical features, and treatment of sarcoptic mange in cats. A few reports have shown that clinical signs of infestation in cats may vary from non-pruritic crusted lesions to itchy and mild lesions, while severe signs are very infrequent.

View Article and Find Full Text PDF
Article Synopsis
  • Several copromicroscopic techniques, like conventional flotation and Mini-FLOTAC, were evaluated for diagnosing parasitic infections in dogs and cats using fecal samples from 205 animals in Italy.
  • The study found that flotation and Mini-FLOTAC methods detected the highest rates of positive samples in both species, with specific larvae only identified by the Baermann test in a few cats.
  • Ultimately, while Mini-FLOTAC can serve as a useful alternative for diagnosing various intestinal and respiratory parasites, Baermann's test remains the top choice for detecting metastrongyloid lungworm infections.
View Article and Find Full Text PDF
Article Synopsis
  • - Aelurostrongylosis, a respiratory disease in cats caused by the parasite Aelurostrongylus abstrusus, varies in severity from mild to severe symptoms and is found globally but is often underestimated in terms of its impact.
  • - Research on this parasite in Brazil is limited, particularly in the southern regions, prompting a study conducted in Vilhena, Rondônia, from April 2020 to February 2021.
  • - The study analyzed fecal samples from 101 cats using specific tests, finding only 2 (1.98%) positive cases for A. abstrusus, with no other lungworms detected, leading to discussions on its clinical and epidemiological significance.
View Article and Find Full Text PDF

The gold standard method for the diagnosis of cat aelurostrongylosis is the detection of first stage larvae with the Baermann's examination. Nevertheless, molecular assays have shown higher diagnostic performances compared to copromicroscopy. This study evaluated the usefulness of an species-specific PCR on different biological samples collected in clinical settings from 100 privately-owned cats in Italy (n.

View Article and Find Full Text PDF

Intestinal helminthes of dogs have a relevant role for health and welfare of canine populations and many of them are zoonotic. Thus, a constant surveillance is pivotal to safeguard companion dogs and human health. Data from faecal examinations of pet dogs obtained in the last six years during the routine activity of the laboratory of Parasitology and Parasitic diseases of the University Teaching Veterinary Hospital of the University of Teramo, Italy, are here reported.

View Article and Find Full Text PDF

Background: Parasitic bronchopneumonia in domestic cats in Europe, which can manifest with moderate to severe clinical signs, is frequently caused by Troglostrongylus brevior. Data on epizootiological and clinical relevance of cat troglostrongylosis have been published in the last decade but treatment options are still limited. Promising effectiveness data have been generated from clinical cases and field trials for a spot-on formulation containing 1% w/v moxidectin and 10% w/v imidacloprid (Advocate, Elanco Animal Health).

View Article and Find Full Text PDF

The lungworm is one of the main causes of respiratory diseases in cats worldwide. This report describes the unusual case of a kitten infected with and presented to a veterinary clinic in Brazil with lethargy, dysphagia, non-ambulatory tetraplegia, and pelvic limbs bilateral myoclonus. The clinical picture of the kitten worsened with generalized flaccid tetraplegia and death a few days after hospitalization.

View Article and Find Full Text PDF

Canine angiostrongylosis by is increasingly reported in both enzootic and previously free areas. The complex pathogenesis of the disease makes the clinical workup challenging. Infected dogs show highly variable clinical pictures, characterized by subclinical to life-threatening general, cardio-respiratory, neurological and/or gastrointestinal signs.

View Article and Find Full Text PDF

Several drivers have recently fostered the expansion of throughout Europe, where Vector-Borne Pathogens (VBPs) are also spreading. However, the level of simultaneous risk of infection is still unknown in canine populations. This study evaluated the simultaneous exposure to and major canine VBPs in dogs of Italy.

View Article and Find Full Text PDF

Canine hepatozoonosis caused by   is an emerging disease in Europe. Clinical pictures vary from subclinical to life-threatening and non-specific clinical signs are predominantly reported. A 2-month-old female puppy originating from Southern Italy was adopted and moved to Northern Italy.

View Article and Find Full Text PDF

The metastrongyloid   has an indirect lifecycle involving gastropod intermediate hosts. The widespread snail   is an efficient intermediate host of . As the temperature may influence the developmental rate of metastrongyloids from first (L1) to the third infective larval stage (L3) inside molluscs, this study evaluated the effect of two controlled temperatures on the development of in .

View Article and Find Full Text PDF

Cats and dogs are treated as family members by most pet owners. Therefore, a high quality of veterinary care and preventive medicine is imperative for animal health and welfare and for the protection of humans from zoonotic pathogens. There is a general perception of cats being treated as "small dogs," especially in the field of clinical parasitology.

View Article and Find Full Text PDF

is the most important respiratory parasite infecting domestic cats worldwide. Nevertheless, most records and epizootiological data come from Europe, whilst poor and fragmentary information are available for other regions, including the Americas. The present article describes the first description of cat aelurostrongylosis from Amazonia, Brazil.

View Article and Find Full Text PDF

Tritrichomonas foetus (Trichomonadida, Tritrichomonadidae) is a parasitic protozoan which causes a diarrheic disease in domestic cats worldwide. The epizootiological and pathogenic impact of this parasite in many geographic locations is still to be unraveled; thus, the present study has investigated the occurrence of T. foetus in cats from central Italy, along with the analysis of risk factors and clinical signs.

View Article and Find Full Text PDF