Publications by authors named "Mariasole Cigoli"
Sci Transl Med
August 2021
Article Synopsis
- Anti-HIV broadly neutralizing antibodies (bNAbs) can engage the immune system and may improve antiviral responses during treatment.
- In a study with SHIV-infected rhesus macaques, bNAbs alone reduced viral load significantly, but most macaques experienced a rebound in virus levels within weeks.
- However, when bNAbs were combined with an anti-αβ monoclonal antibody (Rh-αβ), some macaques showed prolonged control of the virus, suggesting that this combination therapy could enhance the effectiveness of bNAbs.
