Publications by authors named "Mariarosa Gaudio"
Utility of Measuring Circulating Bio-Adrenomedullin and Proenkephalin for 30-Day Mortality Risk Prediction in Patients with COVID-19 and Non-COVID-19 Interstitial Pneumonia in the Emergency Department.
Medicina (Kaunas)
December 2022
: In order to accelerate the risk stratification of patients referred to the Emergency Department (ED) with interstitial pneumonia, it could be useful to provide new and effective laboratory tests for use. The aim of our study was to evaluate the prognostic role of two biomarkers, bio-adrenomedullin (Bio-ADM) and proenkephalin (penKid), in patients with interstitial pneumonia (IP) at ED admission. : In 153 consecutive patients with IP, both from COVID-19 or non-COVID-19 etiology, we measured, in a prospective observational manner, penKid and Bio-ADM at ED admission and after 24 h.
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- The association between celiac disease (CD) and selective immunoglobulin A deficiency (SIgAD) has been recognized for over fifty years, yet accurate diagnosis and monitoring remain challenging.
- The introduction of serological tests revealed that measuring specific IgA antibodies without total serum IgA can miss diagnosing IgA-deficient patients, while specific IgG antibodies may provide additional diagnostic value.
- The 2012 ESPGHAN guidelines improved diagnostic criteria for CD in SIgAD patients but still leave uncertainties regarding patient selection for IgG testing and reliable testing methods, emphasizing the need for improved strategies in diagnosis and management.
Background: In most European eye banks, human donor corneas are microbiologically tested after storage in organ culture conditions, and the tissues that are free of contamination are distributed for transplantation. In this prospective study, 100 donor corneas were tested for microbial contamination after cold storage, corneal culture and corneal deswelling at the Eye Bank of Rome.
Methods: Samples of cold storage medium (EUSOL-C), corneal culture medium (TISSUE-C) and deswelling medium (CARRY-C) were tested after three, seven and one days of corneal storage, respectively.