Publications by authors named "Marianne Samir M Issac"
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Synopsis of recent research by authors named "Marianne Samir M Issac"
- Recent research by Marianne Samir M Issac focuses on the genetic determinants of various diseases, particularly chronic obstructive pulmonary disease (COPD) and cardiovascular conditions, exploring the role of gene polymorphisms in disease susceptibility and therapeutic response.
- Her work includes the investigation of associations between specific genetic markers, such as surfactant protein D and interleukins, with diseases like COPD, as well as examining genetic factors influencing carotid atherosclerosis in end-stage renal disease.
- Additionally, she has contributed to personalized medicine by validating warfarin dosing algorithms based on genetic makeup and analyzing the impact of polymorphisms in the MDR1 and SLCO1B1 genes on statin response, highlighting the importance of genetic factors in optimizing medication efficacy.