Publications by authors named "Marianne Overgaard Hesselager"
Probiotic bacteria are increasingly popular as dietary supplements and have the potential as alternatives to traditional antibiotics. We have recently shown that pretreatment with spp. Lb21 increases the life span of and results in resistance toward pathogenic methicillin-resistant (MRSA).
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- * The study reveals that dynein, a motor protein, facilitates communication between engulfing cells and apoptotic germ cells in the C. elegans germline, influencing the process of apoptosis.
- * Findings highlight that dynein light and heavy chains are essential for proper apoptosis, as their absence disrupts the localization of key apoptotic proteins, suggesting that better understanding of this interaction could lead to new treatments for diseases linked to cell death and engulfment issues.
The gut epithelium formed between an organism and the environment plays an essential role in host-microbe interactions, yet remains one of the least characterized mammalian tissues. Especially the membrane proteins, which are critical to bacterial adhesion, are understudied, because these proteins are low in abundance, and large amounts of sample is needed for their preparation and for undertaking MS-based analysis. The aim of this study was to evaluate three different methods for isolation and preparation of pig intestinal epithelial cells for MS-based analysis of the proteome.
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