Publications by authors named "Marianne Hupe"
Background: In case of high risk of lymph node invasion after endoscopic resection (ER) of superficial esophageal squamous cell carcinoma (SCC), adjuvant chemoradiotherapy (CRT) can be an alternative to surgery. We assessed long-term clinical outcomes of adjuvant therapy by CRT after non-curative ER for superficial SCC.
Methods: We performed a retrospective multicenter study.
Article Synopsis
- The study aimed to compare the effectiveness of ustekinumab and anti-TNF agents as first-line treatments in biologic-naïve patients with luminal Crohn's disease, focusing on clinical response rates at 3 months.
- A total of 206 biologic-naïve patients (156 on anti-TNF agents and 50 on ustekinumab) were evaluated, with response rates at 3 months showing 64% for ustekinumab and 86% for anti-TNF agents, indicating a significant advantage for anti-TNF therapy (P = .01).
- The findings suggest that anti-TNF agents lead to higher response rates within 3 months compared to ustekinumab, although no significant
Background: Few data exist to help select a second biologic agent in patients with refractory ulcerative colitis (UC).
Aim: To compare the efficacy of infliximab (IFX) and vedolizumab (VDZ) in UC patients who failed a first subcutaneous anti-tumor necrosing factor (TNF) agent.
Methods: Consecutive UC patients from 12 French centres starting IFX or VDZ after at least one injection of adalimumab or golimumab have been included in a retrospective study.