Lung cancer screening by low-dose CT scan in France: final results of the DEP KP80 study after three rounds.

Background: In prior randomised controlled trials, lung cancer screening using low-dose computed tomography (LDCT) has been shown to reduce lung cancer mortality and overall mortality. Despite these results, organised screening in France remains a challenge. This study assessed the feasibility and efficacy of lung cancer screening within a real-life context in a French administrative territory.

Pulmonary emphysema quantification at low dose chest CT using Deep Learning image reconstruction.

Purpose: Quantitative analysis of emphysema volume is affected by the radiation dose and the CT reconstruction technique. We aim to evaluate the influence of a commercially available deep learning image reconstruction algorithm (DLIR) on the quantification of pulmonary emphysema in low-dose chest CT.

Methods: We performed a retrospective study of low dose chest CT scans in 54 patients with chronic obstructive pulmonary disease (COPD).

Results of Second Round Lung Cancer Screening by Low-Dose CT scan - French Cohort Study (DEP-KP80).

Introduction: Over the last few years, lung cancer screening by low-dose CT scan has demonstrated a decrease in lung cancer mortality. While this method has been in use since 2013 in the United States of America, no European country has yet implemented a systematic screening program. We hereby report the results from the second round of screening from a French cohort study.

Lung Cancer Screening by Low-Dose CT Scan: Baseline Results of a French Prospective Study.

Background: Lung cancer mortality has been found to decrease significantly with low-dose (LD) computed tomographic (CT) screening among current or former smokers. However, such a screening program is not implemented in France. This study assessed the feasibility of a lung cancer screening program using LD CT scan in a French administrative territory.

Two cases of pneumonitis induced by targeted therapy.

Interstitial pneumonitis is a rare drug adverse effect. We report two cases of cobimetinib-induced and vemurafenib-induced reversible interstitial pneumonitis. Two patients presenting a BRAF-mutated metastatic melanoma were treated with cobimetinib and vemurafenib.