Publications by authors named "Marianna Zolotovskaya"
Article Synopsis
- - Taxanes, like paclitaxel and docetaxel, are key treatments for breast cancer, but how they work and why some patients resist them aren’t fully understood.
- - This study analyzed a huge amount of breast cancer gene expression data to identify 34 genes and 29 pathways that can help distinguish between patients who respond well to taxane treatment and those who don’t.
- - They developed predictive signatures based on gene expression and pathway activation that showed strong potential in identifying treatment responses, indicating a promising step towards more personalized breast cancer therapy.
Uniformly shaped harmonization of gene expression profiles is central for the simultaneous comparison of multiple gene expression datasets. It is expected to operate with the gene expression data obtained using various experimental methods and equipment, and to return harmonized profiles in a uniform shape. Such uniformly shaped expression profiles from different initial datasets can be further compared directly.
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