Publications by authors named "Marianna Gaҫa"
Article Synopsis
- The series examines the pre-clinical assessment of a tobacco heating product called THP1.0, comparing its emissions to traditional cigarette smoke and other next generation products (NGPs).
- There is a risk continuum for tobacco products, with cigarettes being the most harmful and Nicotine Replacement Therapy being the least, indicating THP1.0 may have a reduced risk compared to cigarettes.
- However, while initial data suggests THP1.0's emissions are lower than those from cigarettes and similar to other NGPs, further research is necessary to fully understand its risk profile and long-term impacts.
DNA damage can be caused by a variety of external and internal factors and together with cellular responses, can establish genomic instability through multiple pathways. DNA damage therefore, is considered to play an important role in the aetiology and early stages of carcinogenesis. The DNA-damage inducing potential of tobacco smoke aerosols in vitro has been extensively investigated; however, the ability of e-cigarette aerosols to induce DNA damage has not been extensively investigated.
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