Publications by authors named "Marianna Bravo"

Background And Aim: In surgically altered anatomy (SAA), endoscopic retrograde cholangiopancreatography (ERCP) can be challenging, and it remains debatable the choice of the optimal endoscopic approach within this context. We aim to show our experience and evaluate the technical and clinical success of endoscopic treatment performed in the setting of adverse events (AE) after pancreaticoduodenectomy (PD).

Methods: This study was conducted on a retrospective cohort of patients presenting biliopancreatic complications after PD from 01/01/2012 to 31/12/2022.

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Article Synopsis
  • Endoscopic papillectomy (EP) is considered a safe method for removing ampullary lesions, but information on handling leftover or returning adenomas is limited.
  • In a study of 95 patients who underwent EP from 2011 to 2022, 28.4% showed residual adenomas, and 11.6% experienced recurrences, highlighting the need for ongoing monitoring.
  • Despite complications in 25% of patients, most recurrences were successfully managed endoscopically, suggesting EP is a viable long-term treatment for these tumors.
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  • Endoscopic stenting, particularly using lumen-apposing metal stents (LAMS), is a key treatment for benign biliary strictures, which can recur or cause stent migration.
  • A study involving 70 patients showed a 100% technical success rate and an 85.7% clinical success rate for treating these strictures with bi-flanged LAMS over six years.
  • While 17.1% of patients experienced adverse events like stent migration, LAMS demonstrated effectiveness, especially in post-surgical cases, suggesting it is a safe option for managing short benign biliary strictures.
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Since 2014, we have been using a new endoscopic approach to improve management of biliary adverse events (BAEs) after bilio-digestive anastomosis. We provide an update about our experience at 7 years. Patients with BAEs on hepatico-jejunostomy underwent entero-enteral endoscopic by-pass (EEEB) creation between the duodenal/gastric wall and the biliary jejunal loop.

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Objectives: Studies investigating patients with coeliac disease (CD) on very long-term follow-up are limited. We aimed to evaluate the characteristics of patients with CD diagnosed more than 30 years ago.

Methods: Clinical, histologic, genetic, and demographic data of patients with CD diagnosis made before 1985 were collected and their standardised mortality ratio calculated.

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