Publications by authors named "Mariangela Ferrara"

Article Synopsis
  • Posterior Reversible Encephalopathy Syndrome (PRES) is a condition that typically leads to reversible brain swelling primarily affecting the parieto-occipital areas, often due to issues with blood flow regulation.
  • A case of a woman with multiple health issues, including Turner syndrome and severe hypertension, exhibited unusual symptoms with isolated brain swelling in the pons, as seen on MRI.
  • Successful treatment included medications to lower blood pressure, leading to the resolution of symptoms and return to normal neurological function within three weeks.
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Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiological syndrome, usually reversible, characterized by vasogenic oedema in cerebral posterior regions in patients with autoimmune diseases, nephropathies, hypertensive crisis, eclampsia and exposure to cytotoxic drugs. The main symptoms are: headache, nausea, vomiting, seizures, visual disturbance and altered consciousness. Complications as cerebral hemorrhage and recurrences are rare.

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Background: The impact of educational strategies in the management of adverse treatment effects and drug interactions in adult patients with epilepsy with comorbidities remains undetermined.

Objective: The EDU-COM study is a randomised, pragmatic trial investigating the effect of a patient-tailored educational plan in patients with epilepsy with comorbidity.

Methods: 174 adult patients with epilepsy with chronic comorbidities, multiple-drug therapy and reporting at least one adverse treatment effect and/or drug interaction at study entry were randomly assigned to the educational plan or usual care.

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