F-Fluorocholine PET and Multiphase CT Integrated in Dual Modality PET/4D-CT for Preoperative Evaluation of Primary Hyperparathyroidism.

The present retrospective study evaluates the diagnostic value of integrated F-Fluorocholine positron emission tomography/four-dimensional contrast-enhanced computed tomography (F-FCH PET/4D-CT) as second-line imaging in preoperative work-up of primary hyperparathyroidism (pHPT), and compares F-FCH PET with 4D-CT. Patients with pHPT and negative/discordant first-line imaging addressed for integrated F-FCH PET/4D-CT were retrospectively selected. Sensitivity and detection rate (DR%) of F-FCH PET/CT, 4D-CT, and PET/4D-CT were calculated according to the per patient and per lesion analyses, and afterwards compared.