Publications by authors named "Mariana V Tavares"

Article Synopsis
  • * To reduce mortality, it's essential to develop new methods for reliable screening and early diagnosis of cervical lesions.
  • * Vibrational spectroscopy, especially Fourier transform infrared microspectroscopy, has shown promising results in diagnosing tumors and achieved over 90% accuracy in classifying cryopreserved cervical tissue samples using machine learning.
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  • Adenocarcinoma of mammary gland type (AMGT) of the vulva is a rare condition with unclear causes and no established treatment guidelines due to its low incidence.
  • The text discusses two postmenopausal cases with different treatment strategies, emphasizing the importance of histopathological patterns for accurate diagnosis.
  • Despite both cases showing similar clinical features, they presented distinct pathological and molecular characteristics, highlighting the complexities in diagnosing and treating this rare form of cancer.
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In 2020, approximately 10 million people died of cancer, rendering this disease the second leading cause of death worldwide. Detecting cancer in its early stages is paramount for patients' prognosis and survival. Hence, the scientific and medical communities are engaged in improving both therapeutic strategies and diagnostic methodologies, beyond prevention.

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  • The study examines the outcomes of induced labor versus spontaneous labor in uncomplicated near-term twin pregnancies.
  • It found no significant differences in multiple factors like cervical dilation and maternal/neonatal morbidity between the two groups, except for the caesarean section rates.
  • Induction of labor led to a higher caesarean rate (60.6% vs. 33.3%) and a shorter delivery interval between twins, but overall, induction seems to be a safe option.
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  • Body stalk anomaly is a rare malformation, particularly uncommon in monozygotic twins.* -
  • The case described involves a monoamniotic pregnancy where one fetus had significant abnormalities, including a large abdominal wall defect and absence of lower limbs, while the other fetus appeared normal.* -
  • This report marks the fourth known case of discordant body stalk anomaly in monoamniotic pregnancies, and it's notable for being diagnosed by ultrasound at 11 weeks, making it the second early diagnosis in the first trimester.*
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  • Mitochondrial respiratory chain diseases are genetic disorders that impact energy production in cells, potentially causing symptoms in any organ or tissue at any age, including before birth.
  • The study analyzed data from 44 pediatric patients with mitochondrial disease and found significant differences in birth weight and neonatal morbidity compared to a control group, noting a higher occurrence of intrauterine growth restriction.
  • Results indicate that clinical symptoms can occur regardless of the specific genetic defect, highlighting the need for further research on mitochondrial function during embryonic development to better understand these conditions.
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Article Synopsis
  • Routine vaccination is essential for pediatrics, but it's also important for adults, especially women seeking medical care, who should have their immunizations reviewed and updated.
  • This article addresses concerns regarding vaccinations for pregnant women by discussing their unique immunological changes and the purpose of immunization during pregnancy.
  • It also highlights the indications, contraindications, and risks associated with vaccines in the Portuguese National Vaccine Plan and mentions the significance of vaccination against seasonal influenza and H1N1 during the 2009 pandemic.
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