Publications by authors named "Mariana S Ishikawa"
Article Synopsis
- Understanding the aggregation of amyloid fibers is critical due to its links to degenerative diseases like Alzheimer's and its potential in creating new self-assembling materials.
- L,L-diphenylalanine micro/nanotubes serve as a model for amyloid plaques and exhibit valuable physical properties, with their formation influenced by solvent composition and evaporation.
- Time-resolved Raman spectroscopy revealed that in specific solvents like toluene, ethanol, and acetic acid, the micro/nanotube growth process is autocatalytic rather than nucleation-dominant, highlighting differences in self-assembly mechanisms compared to other solvents.
Multiplex coherent anti-Stokes Raman scattering (MCARS) microscopy was carried out to map a solid tumor in mouse brain tissue. The border between normal and tumor tissue was visualized using support vector machines (SVM) as a higher ranking type of data classification. Training data were collected separately in both tissue types, and the image contrast is based on class affiliation of the single spectra.
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