Publications by authors named "Mariana Roza Marco"
Food Chem Toxicol
October 2024
Article Synopsis
- - Diazepam (DZP) is a sedative used for anxiety and sleep, but it can have negative side effects; researchers aimed to develop nanocapsules to improve its effectiveness and reduce these side effects.
- - The study involved creating and testing DZP nanocapsules using the nanoprecipitation method, ensuring they were stable and effective through various evaluations, including toxicity tests on C. elegans and mice.
- - Results showed that the nanocapsules safely carried DZP, had high drug entrapment efficiency, and produced a hypnotic effect at lower doses without toxicity, making them a promising alternative to traditional DZP.
